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KMID : 0388420040140010195
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Konkuk Journal of Medical Sciences
2004 Volume.14 No. 1 p.195 ~ p.199
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Side Effects of Interferon β-1b at Devic’s Disease
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Kim Jung-Mee
Cho Eun-Kyoung
Cho Jeong-Seon
Choi Yong-Suk
Han Young-Su
Han Jung-Ho
Kim Doo-Eung
Choi Jin-Young
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Abstract
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A 63 year-old woman who had diagnosis of multiple sclerosis complaining left hemiparesis and fluctuating decreased visual acuity in her right eye and abnormal findings in pattern shift visual evoked potentials(PSVEPs) and on T2 weighted MR scanning. We treated her subcutaneously with 250μg interferon (3-lb(ITFß -lb) every other day. There were detected pancytopenia, skin rash, and abnormal liver function test seven days after the therapy. In spite of reducing the dose of interferon injection, abnormal laboratory findings were not returned to normal. Dose adjustment of interferon-I3 for body weight or race, may be helpful to reduce the side effects.
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KEYWORD
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Devic’s disease, Interferon β-1b, side effects
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